WASHINGTON, D.C. – General Stanley A. McChrystal is out as top commander of American forces in Afghanistan.

McChrystal’s resignation was accepted by President Obama during a meeting at the White House Wednesday morning.

“I did so with considerable regret, ” Mr. Obama said in a press conference at 1:40 p.m. (ET)

The four star general came under fire for critical comments made about the administration in an interview with Rolling Stone magazine.

(Gen. Stanley A. McChrystal, left, arrived at the White House on Wednesday morning for a meeting with President Obama/PHOTO-New York Times)

Army General David Petraeus, head of U.S. Central Command, is the president’s pick to replace McChrystal.

Sources say Patraeus, will step down from Central Command.

His appointment has to be confirmed by the Senate.